Therefore, our study focused not only on the relationship between urinary fluoride concentration and the risk of myocardial enzymes (serum CK, serum CK-MB, serum LDH, serum α-HBD, and serum AST) but also on myocardial ischemia and arrhythmia in a population-based cross-sectional study. This evidence concerns the gene HBD and myocardial ischemia.