In recent years, NCAPD3 has been intricately linked to cancer development and progression, particularly in colorectal cancer (Jing et al., 2022a), prostate cancer (Jing et al., 2022b), gastric cancer (Zhang SY et al., 2024), and non-small cell lung cancer (Yang F et al., 2024). This evidence concerns the gene NCAPD3 and cancer.