The study has revealed for the first time a complex of parameters of natural and adaptive immunity which are most important for classification of patients and individuals without psychiatric diseases: the level of some markers of systemic inflammation and activation of humoral immunity (CRP, cortisol, CIC), pro-inflammatory cytokines (IL-1β, IL-8, TNF-α), immunoregulatory proteins (IL-1RA), Th1 immunity cytokines (IFN-γ), Th2 cytokines (IL-4), and immunoregulatory cytokines (IL-10). This evidence concerns the gene IL1B and psychiatric disorder.