In addition, a multicenter observational study of children with a sepsis phenotype characterized by persistent hypoxemia, encephalopathy and shock -which is associated with increased systemic inflammation and endothelial activation- found that those who received 0.5 g/kg or more of intravenous albumin within the first 24 h of care were associated with a higher survival rate (75% vs. 66%) than those who did not after adjusting for confounders (60). The gene discussed is ALB; the disease is Sepsis.