eGFR - estimated glomerular infiltration rate; iMCD - idiopathic multicentric Castleman disease; JAK - Janus kinase; TAFRO - the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype; TNF-α - tumor necrosis factor-alpha. Here, TNF is linked to Thrombocytopenia.