Recently, Tang et al. (2024) showed that deubiquitination of ZMYND8 by ubiquitin carboxyl-terminal hydrolase 7 (USP7) stabilizes the ZMYND8 oncoprotein and stimulates the transcription of target genes ZEB1 and vascular endothelial growth factor A (VEGFA), enhancing the migration and invasion ability of BC cells [179]. Here, ZEB1 is linked to breast cancer.