PNLIP and obesity due to melanocortin 4 receptor deficiency: Notably, thalassiolins A and C, in addition to their antimicrobial effects, exhibit inhibitory activity against nitric oxide synthase, ROS 1 kinase, human pancreatic lipase, and fat mass and obesity-associated (FTO) proteins, making them of interest for the development of new antioxidants and anti-obesity medications [56].