In this sense, zosterabisphenone B induced apoptosis in HCT116 colon cancer cells increasing the levels of cleaved caspases, Poly (ADP-ribose) polymerase (PARP) and BH3 Interacting Domain Death Agonist (BID) proteins and a decrease in Bcl-2 and c-Myc proteins [60]. The gene discussed is BID; the disease is colonic neoplasm.