Due to an X-linked recessive defect involving glucose-6-phosphate dehydrogenase (G6PD), favism is the most common enzyme-deficiency anemia worldwide, and its prevalence varies among ethnic groups with overall lower frequency in the Pacific (2.9%), Europe (3.9%), and the Americas (3.4%) if compared to sub-Saharan Africa (7.5%), the Middle East (6.0%), and Asia (4.7%) [59]. Here, G6PD is linked to deficiency anemia.