In colorectal cancer, mucinous subtypes, including mucinous adenocarcinoma and mucin-rich signet cell variants, are notorious for exuberant lymphocytic response, sometimes described as “Crohn’s-like”, and it is possible that similar patterns in AC may be elucidated in future studies [33]. The gene discussed is MUC5AC; the disease is colon mucinous adenocarcinoma.