Among histologic tumor types, LAMN contained the highest density of both CD3+ and CD8+ lymphocytes as well as I-score, which is a derivative of CD3+ and CD8+ counts performed in a manner analogous to the ImmunoscoreTM (p = 0.008 for CD3+ density and p = 0.03 for IS; Table 2/Figure 3). Here, CD8A is linked to neoplasm.