Caro et al. found that OXCT1 and Acetyl-CoA Acetyltransferase (ACAT1, also known as acetoacetyl Coenzyme A thiolase) were increased in the mitochondria proteome of a metabolomic subtype of DLBCL, the OxPhos-DLBCL subtype patients [31]. Here, ACAT1 is linked to diffuse large B-cell lymphoma.