BCL2 and mantle cell lymphoma: Sanchez-Tillo et al. [23] observed that ZEB1 also played a role in resistance to drugs in mantle cell lymphoma by switching on the genes involved in the proliferation (MYC and MK167), suppressing the proapoptotic (TP53 and BAX) and antiapoptotic (MCL1 and BCL2) pathways, and the membrane transporter proteins involved in drug efflux and influx (gemcitabine, doxorubicin, and cytarabine), thereby facilitating resistance against chemotherapy.