NFE2L2 and esophageal squamous cell carcinoma: Arora et al. highlighted DPP3’s role in esophageal squamous-cell carcinoma (ESCC), showing that its overexpression leads to an increased proliferation, apoptosis, and migration of ESCC cells, while its knockdown reduces these effects and sensitizes cells to oxidative stress and chemotherapy by downregulating NRF2 pathway proteins [100].