Recently, high expressions of MCM3 in various cancers, such as head and neck squamous-cell carcinoma, colorectal, bladder, renal cell carcinoma, medulloblastoma, and ovarian cancer, correlated with malignant properties and cell proliferation, were determined in the literature [55,56,57,58,59,60]. This evidence concerns the gene MCM3 and head and neck squamous cell carcinoma.