For instance, there is a higher expression of MYC in the non-neuroendocrine subtypes of SCLC, and MYC has been shown in murine models of SCLC to drive the transition from the neuroendocrine subtypes SCLC-A and SCLC-N to non-neuroendocrine SCLC-Y [43,44]. The gene discussed is MYC; the disease is small cell lung carcinoma.