When the clinical data of the predicted fc3 patients in TEMPUS and CPTAC3 were considered, it was found that all cancers harbored IDH1 mutations, a frequent somatic mutation commonly found in acute myeloid leukemia (20%), cholangiocarcinoma (20%), chondrosarcoma (80%), and low-grade gliomas (80%) [9]. The gene discussed is IDH1; the disease is cancer.