ITGB2 and neoplasm: Compared to naïve HL-60 human promyelocytic leukemia cells, which cannot be engulfed by tumor cells, differentiated HL-60 (dHL-60) neutrophils, which can be engulfed by tumor cells, express several integrin family genes, such as ICAM-1, ITGAM, ITGB2, ITGAX, and ITGAV, at higher levels [118].