The apparent suicide of cancer cells following the engulfment of neutrophils requires key components of the LAP PI3KC3 complex, including vacuolar protein sorting 34 (VPS34), UV radiation resistance-associated gene protein (UVRAG), and RUN domain and cysteine-rich domain-containing Beclin-1-interacting protein (RUBCN) [118]. Here, PIK3C3 is linked to cancer.