The subunit CNOT7 (CAF1) is increased in the hepatic cell line model of steatosis [178], and the deletion of CNOT7 is associated with a decrease in steatosis and lipogenic genes, including Fasn (Fatty acid synthase), Acaca (Acetyl-CoA Carboxylase alpha Protein), Scd1 (Stearoyl-CoA desaturase 1), Srebf1 (sterol regulatory element-binding protein 1) and Pparg. Here, FASN is linked to steatosis.