In addition to a decrease in tumor marker Ki67 levels, the results also demonstrate that S. officinalis treatment prevented DNA damage by azoxymethane on lymphocytes (by 65%) and colonocytes (by 20%) and by H2O2 on colonocytes (by 28%), while inhibiting azoxymethane-induced the proliferation of mucosal cells by 30.5%. The gene discussed is MKI67; the disease is neoplasm.