A recent study from our group showed the crucial role of osteoimmunological biomarkers in the evaluation of COVID-19 [29], describing a significant role for the RANKL/OPG ratio (the osteoimmunological markers of bone resorption), the bone fragility marker FGF23, and the interaction with two inflammatory markers: the primary cytokine IL-6 and the soluble maker sRAGE. This evidence concerns the gene IL6 and COVID-19.