Patients receiving GLP-1 RAs had a significantly lower rate of pancreatitis at one year (0.1% vs. 0.2%, p = 0.022), three years (0.2% vs. 0.3%, p < 0.001), and five years (0.3% vs. 0.4%, p < 0.001). The gene discussed is GLP1R; the disease is pancreatitis.