It could be inferred from these findings that ethnicity or geographic-related factors other than HLA-A*32:01 influence a proportion of DRESS cases, such as infectious disease epidemiology, antimicrobial consumption, drug interactions, other unrecognized HLA alleles, or immune system mutations that trigger viral reactivation in disease states, specifically HHV-6, which is strongly associated with DRESS. Here, HLA-A is linked to infectious disease.