There are a multitude of biomarkers linked to MS that can be highlighted: biomarkers of axonal damage: NfL, Tau protein, Amyloid-Precursor Protein (APP), Tubulin β (TUB β); biomarkers of neural damage: 14-3-3 Protein, Neuron-Specific enloase (NSE); biomarkers of glial damage: GFAP, S100β Protein, Nitric Oxide (NO) [46]. The gene discussed is APP; the disease is myeloid sarcoma.