After age, sex, comorbidities (diabetes, hypertension, heart failure, cardiac arrhythmia, chronic kidney disease, chronic hepatic disease, and chronic obstructive pulmonary disease), and laboratory tests (abnormal platelet count, total bilirubin and c-reactive protein) were adjusted for, the results indicated that the adjusted HR indicated a trend, but this trend was nonsignificant (p = 0.068, Figure 2). The gene discussed is CRP; the disease is heart failure.