POMC and Hypoglycemia: Based on the paraclinical explorations, other potential causes of hypoglycemia were excluded such as adrenal insufficiency (ACTH and serum cortisol levels in a sample taken at 8.00 a.m. were normal), thyroid dysfunction (normal TSH, FT4, FT3), organ failure (normal kidney and liver function) and sepsis (normal blood counts, normal inflammatory tests), respectively.