Based on the paraclinical explorations, other potential causes of hypoglycemia were excluded such as adrenal insufficiency (ACTH and serum cortisol levels in a sample taken at 8.00 a.m. were normal), thyroid dysfunction (normal TSH, FT4, FT3), organ failure (normal kidney and liver function) and sepsis (normal blood counts, normal inflammatory tests), respectively. The gene discussed is POMC; the disease is Adrenal insufficiency.