A significant difference in RIPK3 expression was observed in the epithelium among the pooled samples from the SJS/TEN patients (average immunofluorescence [IF] intensity: 5590 a.u.), lichen planus (LP) patients (average IF intensity: 1979 a.u.), and normal controls (average IF intensity: 1345 a.u.)(p < 0.0001). The gene discussed is RIPK3; the disease is toxic epidermal necrolysis.