Curcumin has been shown to inhibit the expression of pro-inflammatory mediators, such as C-reactive protein (CRP), TNF-α, IL-1β, and intercellular adhesion molecule-1 (ICAM-1), which play crucial roles in the development and progression of atherosclerosis [100,101,102,103,104,105]. Here, ICAM1 is linked to atherosclerosis.