AQP5 silencing decreases cell invasion by modulating EMT-related proteins in colon cancer and hepatocellular carcinoma (HCC), but also through the downregulation of Wnt/β-catenin and the nuclear factor-kappa B (NF-ĸB) signaling pathways, respectively [71,72]. This evidence concerns the gene AQP5 and malignant colon neoplasm.