Thus, we performed immunofluorescence experiments to label microglia (anti-Iba-1), astrocytes (anti-GFAP), and Aβ species (anti-BAM10, which has an affinity for peptides Aβ1-40 and Aβ1-42, oligomers, fibrillar species and plaques) in the brain of 3xTg-AD mice treated with vehicle and CN (Figure 7F,G,J,K,O,P). This evidence concerns the gene AIF1 and Alzheimer disease.