In our study on thyroid carcinoma, lower levels of ETS1 in the cytoplasm correlated with higher pT status of PTC patients, and lower nuclear levels of ETS1 correlated with the occurrence of metastasis in the local lymph nodes, while no significant correlation was found of total ETS1 amount with any of the tested unfavorable clinicopathological PTC factors. The gene discussed is ETS1; the disease is thyroid gland carcinoma.