TRPM7 was overexpressed in NSCLC cell line A549 after stimulation with epidermal growth factor (EGF), with consequent increase in cell migration: both TRPM7-KO and the use of Waixenicin A counteracted the elevation in TRPM7 levels and had anti-cancer stem cell (CSC) effects [222]. This evidence concerns the gene TRPM7 and cancer.