In a recent study, MDS showed increased concentrations of oligomeric TDP-43 (o-TDP-43) in the plasma of Korean FTD patients with SD compared to those in patients with MCI, early-onset AD (EOAD), late-onset AD (LOAD), idiopathic PD (IPD), and healthy controls [102]. The gene discussed is TARDBP; the disease is frontotemporal dementia.