It is noteworthy that when subjects were categorized based on gut microbiota (i.e., according to the dominant CAG), IL-18 was elevated in individuals with a dominance of the CAG-Pathogen (p = 0.025, MLR) (Table S3), an association also observed in individuals with high BMI (Table S2), and those with abdominal obesity that were cardiometabolically abnormal (Table S4). The gene discussed is IL18; the disease is Abdominal obesity.