Specifically for AML, the pathway analysis linked nine key miRNAs as selected regulators of CRK, MELTF, MECP2, KPNA1, and GSPT1 targets: hsa-let-7b-5p and hsa-let-7a-5p (let-7 family); hsa-let-7d-5p and hsa-miR-124-3p (mir-124 family); hsa-miR-128-3p and hsa-miR-15a-5p (miR-15 family); hsa-miR-196b-5p, hsa-miR-19b-3p, and hsa-miR-210-3p (Figure 9C). This evidence concerns the gene GSPT1 and acute myeloid leukemia.