In human colon cancer cells (HT-29) genistein (200 μgmol/L) decreased the expression of typical EMT molecules (i.e., N-cadherin, Snail2/Slug, ZEB1, ZEB2, FOXC1, FOXC2, and TWIST1), perturbed the Notch-1/NF-κB axis, and induced apoptosis [140]. The gene discussed is SNAI2; the disease is malignant colon neoplasm.