The results demonstrated that TMEM160 knockout significantly reduced the tumor volume from day 20 (p = 0.0006) and continued through the end of the experiment on day 40 (p = 0.01) (Figure 8G) and weight (p = 0.0005) in HeLa cell xenografts in female NOD SCID mice (Figure 8H,I). The gene discussed is TMEM160; the disease is neoplasm.