In this process, since RNA-seq analysis among different breast cancer cell lines illustrated an intense expression for caspase-3 and a significant expression of caspase-7 in TNBC cell lines, including those we used in our assays, apparently upregulation of caspase-3/7 is less likely to be the major source for increased bioactivity of these enzymes in our assays. The gene discussed is CASP7; the disease is breast cancer.