Accordingly, it has recently been shown that the proliferation of MLL/KMT2A-rearranged B-ALL cells was decreased upon MYC depletion and that MYC-protein abundance in MLL/KMT2A-rearranged B-ALL cells was much higher than in non-MLL/KMT2A-rearranged B-ALL cells [29]. This evidence concerns the gene KMT2A and acute lymphoblastic leukemia.