Accordingly, it has recently been shown that the proliferation of MLL/KMT2A-rearranged B-ALL cells was decreased upon MYC depletion and that MYC-protein abundance in MLL/KMT2A-rearranged B-ALL cells was much higher than in non-MLL/KMT2A-rearranged B-ALL cells [29]. The gene discussed is MYC; the disease is acute lymphoblastic leukemia.