However, some of them, such as soluble Suppression of Tumorigenicity 2 (sST2), Growth Differentiation Factor-15 (GDF-15), soluble urokinase Plasminogen Activator Receptor (suPAR), Fatty Acid Binding Protein 4 (FABP4), or mineral metabolism (MM) biomarkers (Fibroblast Growth Factor 23 (FGF23), klotho, phosphorus (P), parathyroid hormone (PTH), or 1-25-dihydroxyvitamin D (calcidiol) have shown promising results in relation to the diagnosis and prognosis of HF. The gene discussed is GDF15; the disease is hydrops fetalis.