Reduced ADAMTS6 gene transcript levels have also been observed in bladder urothelial carcinoma (BLCA), kidney chromophobe (KICH), kidney renal clear-cell carcinoma (KIRC), kidney renal papillary-cell carcinoma (KIRP), skin cutaneous melanoma (SKCM), and uterine corpus endometrial carcinoma (UCEC). The gene discussed is ADAMTS6; the disease is bladder transitional cell carcinoma.