EIF6 and neoplasm: CA1 (Carbonic Anhydrase 1) was downregulated, indicating altered pH regulation in the tumor microenvironment; CCND1 (G1/S-specific Cyclin-D1), CXCL2 (C-X-C Motif Chemokine 2), and EIF6 (Eukaryotic Translation Initiation Factor 6) were upregulated, participating in cell cycle regulation, immune response, and protein synthesis, respectively.