ISY1 and cancer: In the pathway network of the blue module (Figure 4d), TCONS_00011945 (Alias: lnc-CLVS2-2, a lncRNA) was linked to seven mRNAs (ITGA2, ADH1B, ATG16L1, ISY1, ZNF300, GPR161, and RDH11) and enriched in 20 signaling pathways, such as platelet activation, pathways in cancer, proteoglycans in cancer, focal adhesion, PI3K-Akt signaling pathway, metabolic pathways, glycolysis/gluconeogenesis, chemical carcinogenesis, tyrosine metabolism, autophagy—animal, and NOD-like receptor signaling pathway.