In the same year, Hanley et al. [56] compared the plasma cfDI of PCa patients with those of three different control groups: (1) healthy volunteers (HC) under 40 years of age (Ctr1); (2) patients with radical prostatectomy and low PSA six months after surgery (Ctr2); (3) patients with negative prostate biopsy (Ctr3). This evidence concerns the gene KLK3 and posterior cortical atrophy.