After 12 h post-seeding, statistically increased levels of caspase-1 were observed in contact with GF + PTX compared with GF (p < 0.0001) and GFAP + PTX compared with GFAP (p < 0.0001), suggesting the anti-tumor and pro-inflammatory properties of PTX in contact with metabolically active tumor cells. Here, CASP1 is linked to neoplasm.