TNF and colitis: -Its administration mitigates colitis-associated colorectal cancer, as A. muciniphila is associated with the induction of cytotoxic T lymphocytes [121]-Inhibits tumorigenesis by upregulating several metabolic pathways, including glycolysis, fatty acid biosynthesis, and glutamine metabolism, that had previously been downregulated in the mouse lung cancer models [122]-Attenuates chemotherapy-induced intestinal injury and downregulates the production of inflammatory cytokines, including IL1β, IL6, and TNF [123]