-WT and TLR4−/− mice with A. muciniphila + DSS-induced colitis [82]-Acute liver injury mouse model (24 h after 300 mg/kg APAP dosing) + A. muciniphila [89]-Cecal ligation and puncture (CLP)-induced sepsis model: oral gavage of Amuc_1100 in mice before the procedure to induce sepsis [119]-Mouse atopic dermatitis (AD) model: NC/Nga mice with induced AD -> 6 weeks of daily oral gavage of A. muciniphila [120]. The gene discussed is TLR4; the disease is Alzheimer disease.