It is well known that elevated levels of Hb, MCH, and MCHC are associated with increased blood viscosity [65], which induces decreased blood flow to skeletal muscles and fat tissues, contributing to peripheral vascular resistance and elevating the risk of T2DM development, interfering with insulin-mediated glucose uptake [37], and potentially elevating blood pressure [66], thus contributing to the development of HTN [34,38]. The gene discussed is INS; the disease is type 2 diabetes mellitus.