While a degree of skepticism rises when considering the actual bioavailability of (poly)phenols, emerging preclinical evidence suggests that phenolic acids may reduce the release of pro-inflammatory cytokines (such as, TNF-α, IL-6, IL-1β, and TGF-β), inhibit amyloid beta accumulation, and mitigate memory deficits [58]. The gene discussed is IL6; the disease is memory.