For instance, sorghum QL33/QL36 has a relatively high level of Apigeninidin and Caffeic acid polyphenol [44], and sorghum extract QL12 possesses a relatively high level of Luteolinidin and caffeic acid, which has been shown to be effective in the attenuation of AD-related hallmarks such as oxidative stress, Aβ aggregation, mitochondrial dysfunction, and specifically, tau (for caffeic acid) [59,60,61,62,63]. Here, MAPT is linked to Alzheimer disease.