CRP and rheumatoid arthritis: (1) Weight SMD −0.45 (CI −0.71, −0.18).(2) CRP: −50.65 mg/L (−83.4, −18.26), RA patients. Inflammatory biomarkers (SMD −2.33. (CI −3.82, −0.84), p = 0.002, OA + RA patients. RA group (SMD −1.10 [95 % CI −1.71, −0.49], p = 0.0004(3) Joint pain (SMD −0.98; CI −2.90, 0.93), p = 0.31. In a subgroup analysis pooled pain scores in a RA group were (SMD −2.81 CI −3.6, −2.02), p < 0.00001.