Additionally, ellagic acid alleviated neuroinflammation, axonal damage, and demyelination in spinal cord specimens of the experimental autoimmune encephalomyelitis (EAE) group by decreasing the tissue NLRP3 inflammasome, increasing the expression of the myelin basic protein (MBP), and blocking the immunoreactivity of the glial fibrillary acidic protein (GFAP) and ionized calcium-binding adaptor molecule 1 (Iba1) [34]. This evidence concerns the gene GFAP and experimental autoimmune encephalomyelitis.