CASP1 and nasopharyngeal carcinoma: Another recent study demonstrated the anticancer ability of bioactive compounds by regulating pyroptosis in nasopharyngeal carcinoma: tanshinone IIA upregulated the concentration of cleaved GSDMD and caspase-1 and promoted the secretion of inflammatory cytokines including IL-18 and IL-1β in nasopharyngeal carcinoma HK1 cells [55].