TJP1 and colitis: The results showed that the colonic expression of ZO-1 and occludin was significantly lower in colitis mice compared to the Control group, whereas these changes were markedly improved after LF intervention, manifested as the expression of ZO-1 and occludin in the colon of LF + DSS group, with SASP + DSS group being similar to the Control group (Figure 6a).