Concurrently, according to the work from Dahlhoff et al., ANGPTL4 proves to be important in reducing lipid droplet size and mass, suggesting ANGPTL4 mimics therapeutic agents for acne [97], and thus, this could provide some evidence for VD as a possible relieving agent in acne patients via ANGPTL activation [98]. The gene discussed is ANGPTL4; the disease is acne.